Carcinoma showing thymus-like elements invading the trachea

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KRAS, EGFR, PDGFR-α, KIT and COX-2 status in carcinoma showing thymus-like elements (CASTLE)

BACKGROUND CASTLE (Carcinoma showing thymus-like elements) is a rare malignant neoplasm of the thyroid resembling lymphoepithelioma-like and squamous cell carcinoma of the thymus with different biological behaviour and a better prognosis than anaplastic carcinoma of the thyroid. METHODS We retrospectively investigated 6 cases of this very rare neoplasm in order to investigate the mutational s...

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CT and MRI findings of carcinoma showing thymus-like differentiation.

Carcinoma showing thymus-like differentiation (CASTLE) is a rare tumor that occurs in the soft tissue of the neck or in the thyroid gland. We report a case of CASTLE in a 54-year-old man presenting with hoarseness. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a mass enclosing the right carotid artery with the shape of lobulation and invasion to the trachea. The mass was ...

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Well-differentiated thyroid carcinoma invading the larynx and trachea

Larynx and trachea invasion by thyroid cancer is an uncommon but difficult problem. There is no consensus on indication for the extent of surgery, particularly when there is a requirement for airway reconstruction. In general, the surgeon must decide between a complete ablation of the tumor at the cost of large-mutilation and a less radical dissection that leaves residual tumor to be treated wi...

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Intrathyroidal epithelial thymoma: carcinoma showing thymus-like differentiation mimicking squamous cell carcinoma of the thyroid.

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Thyroid Carcinoma Showing Thymic-Like Differentiation Causing Fracture of the Trachea

Thyroid carcinoma showing thymic-like differentiation (CASTLE) comprises a rare neoplasm of the thyroid gland which arises from ectopic thymic tissue or remnants of brachial pouches. CASTLE is regarded as an indolent neoplasm with a favorable prognosis, irrespective of its metastatic potential. Diagnosis is difficult as clinicopathological features have not been yet well-defined. Radiological f...

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ژورنال

عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery

سال: 2006

ISSN: 0022-5223

DOI: 10.1016/j.jtcvs.2006.03.020